• Welcome to AIMed

    An innovative four-year research and
    training programme studying
    Antimicrobial Integrated Methodologies

    Find out more about us
  • Jobs with AIMed

    Discover our latest available vacancies for Early Stage Research Fellows positions

    Search for opportunities
  • AIMed’s training and development

    Summer schools, workshops and training events for Early Stage Research Fellows

    Learn More

Research Programme

Find out how we’re integrating the knowledge and expertise of world-leading scientists.

 

DISCOVER MORE

Training Programme

A programme to improve technical skills, research competencies, professional development and work experience.

FIND OUT MORE

AIMed's Network

We are a multidisciplinary team using cutting-edge technology to develop novel antimicrobial orthopaedic implants.
 

CONTINUE READING

Individual Projects

Find out how you can become an Early Stage Research Fellow (ESR) and participate in a research programme leading to a PhD degree.

EXPLORE OUR PROJECTS

This website is here to help document AIMed’s aims and objectives, its ongoing work, and disseminate its scientific outcomes. We will also be communicating and organising outreach activities to a wider scientific community and the general public via this website. We are very excited about the future of this project, and our website means that YOU can be a part of it. Please feel free to leave comments.

Researchers
trained in
inter-disciplinary
environments
are needed, now!

AIMed has recognised that there is an urgent need for inter-disciplinary trained researchers with knowledge of effective antimicrobial methodologies. Some of the skills we are offering include:

  • The use of advanced tools to effectively identify and understand mechanisms and behaviours of peptides in interaction with bacteria and cells
  • The technical skills to modify metals, ceramic and polymer surfaces using chemical and physical methods
  • The analysis of data and the use of depth and breadth of expertise and experience across the engineering life science interface, combined with the necessary transferable skills to communicate and work effectively across disciplinary and sectoral boundaries

Such a cadre of skilful researchers will lead to faster development and adoption of antibiotic-free methodologies and thus an effective alternative to antibiotic treatment of orthopaedic infections.

AIMed as a Marie Sklodowska-Curie Innovative Training Network (MSCA-ITN)

The Innovative Training Networks (ITN) aim to train a new generation of creative, entrepreneurial and innovative early-stage researchers, able to face current and future challenges and to convert knowledge and ideas into products and services for economic and social benefit. ITNs support competitively selected joint research training and/or doctoral programmes, implemented by partnerships of universities, research institutions, research infrastructures, businesses, SMEs, and other socio-economic actors from different countries across Europe and beyond.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement AIMed No 861138.

The increase in infections by antibiotic-resistant bacteria has become of
great concern for the general public.

The increase in infections by antibiotic-resistant bacteria has become of great concern in hospitals, especially after orthopaedic surgical procedures. The extra costs due to antibiotic resistance have recently been estimated at USD 1000 per infected patient. The risk of re-infection during revisional surgery is far greater than that of primary infection, which is variously estimated to fall around 2%, depending on the type of the prosthetic implant, patient condition, clinical setting and surgical procedure1. The overall infection rates associated with such surgery are approximately 5% for fracture-fixation devices, 2% for primary joint replacements and at least 14% of the total hip and knee revisions. The problems associated with antibiotic resistant bacteria have been exacerbated in recent years by the slowing rate at which new antibiotics are discovered – since 1998, only ten new antibiotics have been approved, only two of which have new targets of actions.

____
1Kenneth E. Thorpe, Peter Joski, Kenton J. Johnston Health Affairs 2018; 37(4)

 
 

Staphylococcus epidermidis biofilm on nanohydroxyapatite surface
 
 
 

Ref: Barros J et al. A modular reactor to simulate biofilm development in orthopedic materials. INTERNATIONAL MICROBIOLOGY (2013) 16:191-198 doi: 10.2436/20.1501.01.193 ISSN 1139-6709 www.im.microbios.org

AIMed's beneficiaries and partners